Colorado ranks third in the nation for its investment in technology and science assets, according to the Milliken Institute.
The state ranks behind Massachusetts and Maryland but before California and Utah.
The institute says that with international competition and tight federal budgets, the states that are investing in high-tech jobs will be better poised for the future.
Colorado also ranked third in 2008, the last time the Milliken Institute did the study.
The 2010 rankings look at 79 indicators that are categorized into five components: research and development, risk capital and entrepreneurial infrastructure, human capital investment, technology and science workforce and technology concentration.
Rounding out the top ten: Washington, New Hampshire, Virginia, Connecticut and Delaware.