Depression hinders HIV treatment protocols, but effective medication reverses that outcome.

Kaiser Permanente published the information from the largest study of its kind in the Journal of Acquired Immune Deficiency Syndromes.

It looked at 3,359 HIV-infected patients across the nation to measure the effects of depression – with and without selective anti-depression medication – on patient use of drugs and therapy.

The researchers examined patient’s adherence to the anti-viral therapy and their T-cell counts during a 12-month period. The study found that depressed patients – 42 percent of the total group – did not take all their medication and had a lower response rate.

Those on anti-depressive medication, however, had the same outcomes as patients who were not diagnosed with depression.